Clin Assoc Prof Joan Khoo

Clinical A/Prof Joan Khoo graduated from the National University of Singapore and completed her specialty training in Endocrinology in Changi General Hospital (CGH). After post-specialist fellowship training in the endocrinology of obesity and appetite regulation at the Royal Adelaide Hospital in Australia, she has been involved in the multidisciplinary management of obese patients in CGH and the community in the eastern part of Singapore in the ECHO (Eastern Community Health Outreach) program. She is currently the Chief & Senior Consultant of the Endocrinology Department at Changi General Hospital and was formerly the Director of the Diabetes Centre.

Her clinical and research interests include diabetes, obesity and weight management. She is a Fellow of the Academy of Singapore (Chapter of Endocrinologists) and of the Royal College of Physicians (UK Edinburgh).

• FRCP (Edin.), Royal College of Physicians (Edinburgh) 2017
• MMed (Int. Med), Singapore National University of Singapore 2004
• MRCP (UK), Royal College of Physicians (Edinburgh) 2004
• MBBS, National University of Singapore (NUS) 2000

• Chief, Department of Endocrinology, Changi General Hospital 2014 – Present
• Deputy Chair, Clinical Trials and Research Unit, Changi General Hospital 2014 – Present
• Hon. Secretary/Board Member, Chapter of Endocrinologists, Academy of Medicine Singapore 2017 – 2023 / 2015 – 2023
• EMSS Secretary 2010 – 2011
• EMSS ExCo Member: 2006 – 2007
• Council Member, Singapore Association for the Study of Obesity (SASO) 2015 – Present
• Director, Diabetes Centre, Changi General Hospital 2011 – 2013

• SingHealth Residency (Internal Medicine) Outstanding Faculty Award, 2022, 2017, 2013
• Singapore Health Quality Service Star Award, 2022
• Singapore Health Quality Service Hero Award, 2021
• Dean's Teaching Award, Yong Loo Lin School of Medicine, National University of Singapore, 2018, 2016
• Singapore Medical Journal Reviewer Recognition Award, 2018, 2017, 2012, 2011, 2010
• SingHealth Residency Outstanding Faculty (Endocrinology) Award, 2016
• Eastern Health Alliance Caring Awards (Star), 2014
• Eastern Health Alliance Best Educator for Medical (Postgraduate) Award, 2013
• Gold Service Award, Changi General Hospital, 2013
• Eastern Health Alliance Caring Awards (Gold), 2013
• SingHealth Quality Assurance Award (Silver), 2011
• SingHealth Talent Development Fund Medical Publication Award, 2011
• Travel grant for Asian Session of the 52nd Meeting of the Japan Diabetes Society, 2009
• Lalor Foundation International Travel Award of the American Society of Andrology, 2009
• SingHealth Best Registrar Award, 2007
• Medical Alumni Association Bronze Medal, 1998
• Robert Lin Memorial Bronze Medal, 1998
• Beecham Book Prize (Microbiology), 1997
• NUS Faculty of Medicine Dean's List, 1996, 1997, 1998, 2000

• Endocrinology
• Diabetes
• Obesity and weight management

• Tay D, Chua M, Khoo J. Validity of the short form 5 item Problem Area In Diabetes (PAID 5) questionnaire as a depression screening tool in type 2 diabetes mellitus. J Diabetes Investig. 2023
• Khoo J et al.  Effects of water stably-enriched with oxygen as a novel method of tissue oxygenation on mitochondrial function, and as adjuvant therapy for type 2 diabetes in a randomized placebo-controlled trial. PLoS One. 2021;16: e0254619.
• Khunti K, Kosiborod M, Kim DJ et al; CVD-REAL Investigators and Study Group. Cardiovascular outcomes with sodium-glucose cotransporter-2 inhibitors vs other glucose-lowering drugs in 13 countries across three continents: analysis of CVD-REAL data. Cardiovasc Diabetol 2021 31; 20:159.
• Kohsaka S, Lam CSP, Kim DJ et al; CVD-REAL 2 Investigators and Study Group. Risk of cardiovascular events and death associated with initiation of SGLT2 inhibitors compared with DPP-4 inhibitors: an analysis from the CVD-REAL 2 multinational cohort study. Lancet Diabetes Endocrinol. 2020; 8:606-615
• Khoo J, et al. Randomized trial comparing effects of weight loss by liraglutide with lifestyle modification in non-alcoholic fatty liver disease. Liver Int 2019; 39:941-949
• Khoo J and Cheong M, 2018.  Meal replacements for weight loss in obesity. Hankey C, Advanced Nutrition and Dietetics in Obesity, John Wiley & Sons, Ltd, Chichester, UK, 1, 150-156
• Khoo J et al. Comparative effects of liraglutide 3 mg versus structured lifestyle modification on body weight, liver fat and liver function in obese patients with non-alcoholic fatty liver disease: a pilot randomized trial. Diabetes Obes Metab 2017; 19:1814-1817
• Khoo J et al. Exercise-induced weight loss is more effective than dieting for improving adipokine profile, insulin resistance and inflammation in obese men. Int J Sport Nutr Exerc Metab 2015; 25: 566-575
• Khoo J et al.  Comparing effects of meal replacements with isocaloric reduced-fat diet on nutrient intake and lower urinary tract symptoms in obese men. J Hum Nutr Diet 2014; 27:219-226
• Fock KM, Khoo J. Diet and exercise in management of obesity and overweight. J Gastroenterol Hepatol.2013; 4:59-63
• Khoo J et al. Comparing effects of low- and high-volume moderate-intensity exercise on sexual function and testosterone in obese men. J Sex Med 2013;10:1823-32
• Khoo J, Chen RYT, Wittert GA 2012, Obesity. Sinclair AJ, Morley JE, Vellas B, in Pathy's Principles and Practice of Geriatric Medicine, Volume 1 & 2. John Wiley & Sons, Ltd, Chichester, UK, 5, 237-248
• Khoo J et al Comparing effects of a low-energy diet and a high-protein low-fat diet on sexual and endothelial function, urinary tract symptoms, and inflammation in obese diabetic men.  J Sex Med 2011; 8:2868-75
• Khoo J et al.  Effects of a low-energy diet on sexual function and lower urinary tract symptoms in obese men. Int J Obes 2010; 34:1396-403