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Rosuvastatin

Crestor


Uses


What is Rosuvastatin for?

Rosuvastatin belongs to the class of medications called Statins (also known as HMG-CoA reductase inhibitors). Statins lower the amount of ‘bad cholesterol’ (low density lipoprotein or LDL-cholesterol) and ‘fat’ (triglyceride) in the blood as well as increase the amount of ‘good cholesterol’ (high density lipoprotein or HDL-cholesterol).

High ‘bad cholesterol’ levels can cause your blood vessels to clog up and lead to chest pain (angina), heart attack or stroke. Hence, statins may reduce your risk for heart attack and stroke.

How should I take or use Rosuvastatin?

  • Do not stop taking your medication without checking with your healthcare professional. If you stop taking your medication, your ‘bad cholesterol’ level may rise again.
  • You may take this medication with or without food.

What should I do if I forget to take or use Rosuvastatin?

If you miss a dose, take the missed dose as soon as you remember. If it is almost time for your next dose, take only the usual dose. Do not double your dose or use extra medication to make up for the missed dose. 


Precaution


What precautions should I take when taking or using Rosuvastatin?

Inform your healthcare professional if:

  • You are allergic to this medication or any of the other ingredients of this medication
  • You are allergic to any other statins, or to any other medications
  • You are pregnant, planning to have a baby or breastfeeding
  • You have liver or kidney problems

What food or medication should I avoid when I take or use Rosuvastatin?

Avoid taking a supplement called red yeast rice as this supplement may increase the risk of side effects.

Avoid or limit drinking alcohol to less than 3 drinks a day. Drinking too much alcohol may raise your chance of liver disease.

Some medications may interact with statins and affect their effectiveness or increase the risk of side effects. However, these medications may also be important for your treatment. Inform your healthcare professional of the other medications you are currently taking. Examples include:

  • Warfarin, a blood thinning medication
  • Medications for bacterial infections (e.g. clarithromycin, erythromycin)
  • Medications for fungal infections (e.g. itraconazole, ketoconazole)

Consult your healthcare professional if you are unsure whether your existing medications can be taken together with statin.


Side Effects


What are some common side effects of Rosuvastatin?

  • Mild muscle aches or weakness, or feeling tired
  • Stomach disturbances such as stomach pain, constipation, diarrhea
  • Headache, joint pain or back pain

Inform your healthcare professional if these side effects do not go away and become bothersome to you.

Very rarely, Statin may cause muscle or liver problems. Stop this medication and see a doctor immediately if you notice any of these symptoms:

  • Breakdown of muscles - Unexplained, severe muscle pain that does not go away, muscle weakness or cramps all over your body, or dark brown urine
  • Liver injury - Dark brown urine, light coloured stools (pale grey/clay coloured), nausea, vomiting, loss of appetite, yellowing of skin or eyes     

The symptoms of a drug allergy include one or more of the following:

  • Swollen face/eyes/lips/tongue
  • Difficulty in breathing
  • Itchy skin rashes over your whole body

If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.


Handling


How should I store Rosuvastatin?

  • Keep away from children
  • Keep in a cool, dry place, away from direct sunlight
  • Throw away all expired medications.

How do I throw away Rosuvastatin safely?

Pack this medication into a black trash bag and seal it tightly before throwing into the rubbish chute or bin.

Disclaimers

Please take note that the above is not a complete list of all possible side effects. If you have any concerns about your medication or if you have other side effects that you think are caused by this medication, please consult your doctor or pharmacist.

If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.

This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System, and SingHealth), community pharmacies (Guardian, Unity, and Watsons), and the Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.

Last Updated on July 2019



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