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Dacarbazine


Uses


What is Dacarbazine for?

Dacarbazine is an intravenous chemotherapy used alone or in combination with other agents for the treatment of certain types of cancer.


Precaution


What precautions should I take when taking or using Dacarbazine?

  • Avoid prolonged exposure to sunlight as Dacarbazine may cause increased sensitivity to sunlight. The use of a sunscreen and/or protective clothing may be helpful.

Side Effects


What are some common side effects of Dacarbazine?

Early side effects

  • Nausea, vomiting and loss of appetite may occur.
    There are medications available, which may prevent or decrease these side effects. If you are given these medications, take them as directed.
  • Diarrhea may occur.
  • Pain at the site of injection may occur.
  • Facial flushing or tingling may occur during treatment. This should only last for a few minutes.
  • Red, itchy skin rash may appear.
  • Flu-like symptoms may occur such as mild fever, muscle ache and tiredness.

Delayed side effects

  • A drop in the white blood cell counts may occur 10 to 14 days after treatment.
  • Temporary hair loss or thinning may begin 2 to 3 weeks after treatment.

Inform your doctor if any of the following occurs:

  • Fever of 38°C or higher.
  • Sore throat, hoarseness or mouth sores.
  • Redness, pain or swelling at injection site.
  • Unusual bleeding, bruising or black tarry stools.

Disclaimers

Please take note that the above is not a complete list of all possible side effects. If you have any concerns about your medication or if you have other side effects that you think are caused by this medication, please consult your doctor or pharmacist.

If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.

This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System, and SingHealth), community pharmacies (Guardian, Unity, and Watsons), and the Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.

Last Updated on October 2017



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