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Abiraterone

Zytiga®


Uses


What is Abiraterone for?

Abiraterone is a medicine given to patients with castrate-resistant prostate cancer. It works by decreasing the amount of androgens in your body and is usually given with prednisolone.

How should I take or use Abiraterone?

It is a tablet taken by mouth, once daily on an empty stomach i.e. either 1 hour before or 2 hours after food. You may take it with a glass of water or juice.

What should I do if I forget to take or use Abiraterone?

If you miss a dose of Abiraterone, skip the missed dose and go back to your usual dosing time. Do not make up for the missed dose by taking 2 doses at once.


Precaution


What precautions should I take when taking or using Abiraterone?

  • Inform your doctor or pharmacist if you:
    • Are on any other medicines e.g. warfarin
    • Have any other medical conditions e.g. heart problems, high blood pressure
  • Use effective birth control during treatment and for at least 1 week after stopping treatment

Side Effects


What are some common side effects of Abiraterone?

  • Joint and muscle pain and weakness
  • Swelling of the leg or feet
  • Hot flushes
  • Headache, giddiness
  • Diarrhea or heartburn
  • High blood pressure
  • Increased blood sugar levels

Inform your doctor if any of the following occurs:

  • Excessive giddiness, weakness, light-headedness or confusion
  • Severe headache
  • Severe muscle or joint pain
  • Severe leg or feet swelling
  • Fast or irregular heartbeat
  • Fever (>37.5°C) accompanied by flu-like symptoms
  • Pain on urination
  • Yellowing of the skin or eyes, or having dark tea-coloured urine

Handling


How should I store Abiraterone?

  • Keep away from children
  • Keep in a cool, dry place, away from direct sunlight
  • Store at room temperature

How should I handle Abiraterone safely?

Women of child-bearing potential should wear gloves while handling this medicine.


For more information


What should I do if I overdose?

If you overdose on this medicine, inform your doctor immediately.

Disclaimers

Please take note that the above is not a complete list of all possible side effects. If you have any concerns about your medication or if you have other side effects that you think are caused by this medication, please consult your doctor or pharmacist.

If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.

This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System, and SingHealth), community pharmacies (Guardian, Unity, and Watsons), and the Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.

Last Updated on January 2021



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