Dr Michael Lau Chin Shern

Dr Michael Lau is an Associate Consultant with the Department of Laboratory Medicine at Changi General Hospital (CGH). He graduated with his MBBS from the National University of Singapore (NUS) Yong Loo Lin School of Medicine in 2010 and went on to obtain his specialist certifications in Internal Medicine from the Royal College of Physicians in 2016. Dr Lau is also certified in Chemical Pathology by the Royal College of Pathologists from the United Kingdom.

Dedicated to advancing medicine, Dr Lau has published original articles in international journals and has presented his findings at various local conventions. He won the Singapore Association of Clinical Biochemists (SACB) Asia-Pacific Federation for Clinical Biochemistry and Laboratory Medicine (APFCB) Scholarship in 2019, and was awarded the Best Platform Presentation Award at the SingHealth 7th Pathology Academic Clinical Programme (ACP) Research Day 2020.

• FRCPath(UK), 2024
• MRCP(UK) (Internal Medicine), 2016
• MBBS, Singapore, 2010

• Platform Presentation – 1st Runner Up, SingHealth Duke-NUS 9th Pathology ACP Research Day, 2022
• Platform Presentation – 2nd Runner Up, SingHealth Duke-NUS 8th Pathology ACP Research Day, 2021
• Hero Award, Singapore Health Quality Service Awards, 2021
• Best Platform Presentation Award, SingHealth Duke-NUS 7th Pathology ACP Research Day, 2020
• Asia-Pacific Federation for Clinical Biochemistry and Laboratory Medicine (APFCB) Scholarship, Singapore Association of Clinical Biochemists (SACB), 2019

• Lau CS, Aw TC. FOURTH UNIVERSAL DEFINITION OF MYOCARDIAL INFARCTION. Austin Cardio & Cardiovasc Case Rep 2018; 3(3).
• Lau CS, Aw TC. Thyroid function testing: Why, what and when. J Otolaryngol Res 2019; 2(1): 128.
• Lau CS, Aw TC. Biotin effects on thyroid function tests – Facts, fancies and fallacies. J Otolaryngol Res 2019; 2(1): 126.
• Lau CS, Tong CH, Goh R, Aw TC. Evaluation of a New Point-of-Care HbA1c Assay: The Pixotest. International Journal of Clinical Chemistry and Laboratory Medicine 2019; 5(4): 1-5.
• Lau CS, Aw TC. HbA1c in the diagnosis and management of diabetes mellitus: An update. Diabetes Updates 2020; 6(1): 1-4.
• Lau CS, Aw TC. A Current Approach to Hyperprolactinemia. Int Arch Endocrinol Clin Res 2019; 5(1): 018.
• Lau CS, Aw TC. Lp(a) as a Cardiovascular Risk Biomarker. Int J Cardiol Cardiovasc Med 2020;3(3): 130.
• Lau CS, Aw TC Re-Evaluation of a New Point of Care Device for Lipid Panel Analysis: the Pixotest. Endocrinology and Diabetes Open Access 2020; 3(1): 114.
• Lau CS, SP Hoo, SF Yew, SK Ong, LT Lum, PY Heng, JG Tan, MS Wong, TC Aw. Evaluation of an electrochemiluminescent SARS-CoV-2 antibody assay. The Journal of Applied Laboratory Medicine 2020; 5(6): 1313-23.
• Lau CS, Kamaludin NA, Aw TC. Laboratory practice in the face of Covid-19. Proceedings of Singapore Healthcare 2021, 30(2): 170-4.
• Lau CS, Oh HML, Hoo SP, YL Liang, SK Phua, Aw TC. Performance of an automated chemiluminescence SARS-CoV-2 Ig-G assay. Clinica Chimica Acta 2020; 510: 760-6.
• Lau CS, Joseph R, Aw TC. Screening for Congenital Hypothyroidism. Ann Acad Med Singap 2020; 49(12): 934-6.
• Lau CS, Lim M, Hoo SP, Gan C, Aw TC. Faster HbA1c Turnaround Times Using a Dedicated Analyzer Based on Turbidimetric Inhibition Immunoassay Technology. J Appl Lab Med 2021; 6(3): 729-34.
• Lau CS, Aw TC. The Importance of macroprolactin in the diagnosis of hyperprolactinemia. Series Endo Diab Met 2021; 3(3): 75-9.
• Lau CS, Hoo SP, Liang YL, Phua SK, Aw TC. Performance of two rapid point of care SARS-COV-2 antibody assays against laboratory-based automated chemiluminescent immunoassays for SARS-COV-2 IG-G, IG-M and total antibodies. Pract Lab Med 2021; 24: e00201.
• Lau CS, Hoo SP, Liang YL, Phua SK, Aw TC. Performance of an automated chemiluminescent immunoassay for SARS-COV-2 IgM and head-to-head comparison of Abbott and Roche COVID-19 antibody assays. Pract Lab Med 2021; 25: e00230.
• Lau CS, Loh WJ, Phua SK, Aw TC. A Contemporary Evaluation of Calculated and Directly Measured LDL. Jap J Clin & Med Res 2021; 1(2): 1-11.
• Lau CS, Hoo SP, Koh JMJ, Phua SK, Aw TC. Performance of the Roche IL-6 chemiluminescent immunoassay in patients with COVID-like respiratory symptoms. J Virol Methods 2021; 296: 114224.
• Lau CS, Phua SK, Liang YL, Oh MLH, Aw TC. Early Pfizer Covid-19 Vaccine Elicited Spike Antibody (total, IgG, IgM) Responses Compared to Chemiluminescent Neutralizing Antibodies. Ann Microbiol Res 2021; 5(1):126-32.
• Lau CS, Phua SK, Liang YL, Oh MLH, Aw TC. BNT162b2 mRNA COVID-19 Vaccine Elicited Antibody Responses in COVID-19-naïve Subjects. J Exp Pathol 2021; 2(3): 117-27.
• Lau CS, Wong MS, Hoo SP, Heng PY, Phua SK, Aw TC. Performance of the Roche/Snibe electrochemiluminescent anti-SARS-COV-2 spike assays compared to the Roche/Abbott IgG nucleocapsid and Abbott IgM spike assays. Pract Lab Med 2021; 27: e00257.
• Lau CS, Phua SK, Liang YL, Oh HML, Aw TC. Robust SARS‐CoV‐2 Antibody Responses in Asian COVID‐Naïve Subjects 180 Days after Two Doses of BNT162b2 mRNA COVID‐19 Vaccine. Vaccines 2021; 9(11): 1241.
• Lau CS, Aw TC. Disease prevalence matters: Challenge for SARS-CoV-2 Testing. Antibodies (Basel) 2021; 10(4): 50.
• Lau CS, Phua SK, Hoo SP, Jiang B, Aw TC. Evaluation and Validation of the Roche Elecsys SARS-CoV-2 Antigen Electro-Chemiluminescent Immunoassay in a Southeast Asian Region. Vaccines 2022; 10(2): 198.
• Lau CS, Phua SK, Liang YL, Oh MLH, Aw TC. SARS-CoV-2 Spike and Neutralizing Antibody Kinetics 90 Days after Three Doses of BNT162b2 mRNA COVID-19 Vaccine in Singapore. Vaccines 2022; 10(2): 331.
• Lau CS, Aw TC. SARS-CoV-2 Antigen Testing Intervals: Twice or Thrice a Week? Diagnostics 2022; 12(5): 1039.
• Lau CS, Oh MLH, Phua SK, Liang YL, Li Y, Huo J, et al. Kinetics of the Neutralizing and Spike SARS-CoV-2 Antibodies following the Sinovac Inactivated Virus Vaccine Compared to the Pfizer mRNA Vaccine in Singapore. Antibodies 2022; 11(2): 38.
• Lau CS, Liang YL, Phua SK, Murtagh G, Hoefer IE, Stokwielder RH, et al. Performance of the Abbott Architect Immuno-Chemiluminometric NT-proBNP Assay. Diagnostics 2022; 12(5): 1172
• Chionh CY, Poh CB, Roy DM, Koduri S, Chow BL, Tan PT, et al. Serum anion gap revisited: a verified reference interval for contemporary use. Intern Med J 2022; 52(9): 1531-7.
• Lau CS, Oh MLH, Phua SK, Liang YL, Aw TC. 210-Day Kinetics of Total, IgG, and Neutralizing Spike Antibodies across a Course of 3 Doses of BNT162b2 mRNA Vaccine. Vaccines 2022; 10(10): 1703.
• Lau CS, Thundyil J, Oh MLH, Phua SK, Liang YL, Li Y, et al. Neutralizing and Total/IgG Spike Antibody Responses Following Homologous CoronaVac vs. BNT162b2 Vaccination up to 90 Days Post-Booster. Antibodies 2022; 11(4): 70.
• Seah S, Tan YK, Teh K, Loh WJ, Tan PT, Goh LC, Malakar RD, Aw TC, Lau CS, et al. Proton-pump inhibitor use amongst patients with severe hypomagnesemia. Front Pharmacol 2023; 14: 1092476.
• Lau CS, Aw TC. Considerations in understanding vaccine effectiveness. Vaccines 2023; 11(1): 20.
• Loh WJ, Soh SH, Tun MH, Tan PT, Lau CS, Tavintharan S, Watts GF, Aw TC. Elevated Remnant Cholesterol and Non-HDL Concentrations from Real World Laboratory Results: A crosssectional study in Southeast Asians. Front Cardiovasc Med 2024; 11: 1328618.
• Lau CS, Oh HML, Aw TC. Reflections on COVID-19: A Literature Review of SARS-CoV-2 Testing. Vaccines (Basel) 2025; 13(1): 9.

Letters/Editorials/Abstracts

• Lau CS, Aw TC. Response to M Mariathas, R Allan, S Ramamoorthy et al, True 99th centile of high sensitivity cardiac troponin for hospital patients: prospective, observational cohort study. BMJ 2019, 364: I729.
• Lau CS, Aw TC.  Editorial: TRAB Measurements: Ready for prime time? Int J Endocrinol Metab Disord 2019; 5(2).
• Lau CS, Aw TC. Rapid Response Re: Thyroid hormones treatment for subclinical hypothyroidism: a clinical practice guideline. Response with regards to Bekkering GE, et al. Thyroid hormones treatment for subclinical hypothyroidism: a clinical practice guideline. BMJ 2019; 365: I2006.
• Lau CS, Aw TC. Comment: Application of High-Sensitivity Troponin in Suspected Myocardial Infarction. N Engl J Med 2019; 381(25): 2482.• Zeng WL, King TFJ, Aw TC, Lau MCS. The Clinical Significance and Utility of Routine Screening for Macroprolactin in Patients With Hyperprolactinemia. J Endocr Soc 2021; 5(1): A636.
• Lau CS, Aw TC. Frequent Severe Acute Respiratory Syndrome Coronavirus 2 Antigen Testing in a Disease-Free Population. J Infect Dis 2021; 224(11): 1986-7.