Dr Tan Seow Yen

MBBS, MMed, MRCP (UK), FAMS

Senior Consultant

Changi General Hospital

Specialty: Infectious Diseases

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About

Education and Training

Professional Appointments and Committee Memberships

Awards

Research Interests

Publications

Conditions Treated By This Doctor

Community Acquired Infections Dengue Fever Hospital acquired infections Human Immunodeficiency Virus (HIV) and Acquired Immune Deficiency Syndrome (AIDS) Infections with multidrug resistant organisms (MDROs) Infective Endocarditis Meliodosis Mosquito Borne Infections Pneumonia Urinary Tract Infection

Clinical Appointments

Senior Consultant

Infectious Diseases

About

Dr Tan Seow Yen is a Senior Consultant with the Department of Infectious Diseases at Changi General Hospital (CGH). She obtained her Master of Medicine in Internal Medicine in 2012, and completed her Master of Public Health from the National University of Singapore (NUS) Saw Swee Hock School of Public Health in 2024.

Dr Tan is committed to providing comprehensive, patient-centred care with expertise in managing complex infections as well as antimicrobial stewardship. With extensive clinical experience, she has lead initiatives to safeguard patient safety and enhance quality of care. Passionate about education and training, Dr Tan is actively involved in mentoring healthcare professionals, fostering a collaborative environment to enhance clinical excellence and public health preparedness. She holds multiple academic appointments, including Physician Faculty for the SingHealth Infectious Diseases Residency Programme and Adjunct Assistant Professor at the NUS Saw Swee Hock School of Public Health.

Dedicated to delivering evidence-based care, Dr Tan works closely with multi-disciplinary teams to ensure the best outcomes for patients and the broader hospital community. Her contributions to medical excellence were recognised with the Gold Award at the Singapore Health Quality Service Award in 2025.

Education and Training

MPH, Singapore, 2024
MRCP (UK), 2012
MMed (Internal Medicine), 2012
MBBS, Singapore, 2008

Professional Appointments and Committee Memberships

Director, Training & Education Division, Communicable Diseases Agency, 2025 – Present
Member, Infection Prevention & Control Committee, 2017 – Present
Member, Society of Infectious Disease (Singapore), 2013 – Present

Awards

Gold Award, Singapore Health Quality Service Award, 2025
Distinguished Young Leader Award, SingHealth Excellence Awards, 2022
Public Administration Medal (Bronze), National Awards (COVID-19), 2022
Star Award, Singapore Health Quality Service Award, 2022
Hero Award, Singapore Health Quality Service Award, 2021
Best Team Award (Merit), Singapore Health Quality Service Award, 2021
Outstanding Faculty Award, Residency in SingHealth Excels (RiSE), 2020

Research Interests

Hospital Acquired Infections
Healthcare Associated Infections
Multi Drug Resistant Organisms
Healthcare Epidemiology

Publications

Chan SLS, Hsieh MKH, Mok JWL, Kong TY. Delayed prosthetic seroma: a localized inflammatory response to COVID vaccination and infection? Eur J Plast Surg. 2023;46(1):125-128. doi: 10.1007/s00238-022-02031-3. Epub 2023 Jan 5. PMID: 36624820; PMCID: PMC9813890

Chan SLS, Mok JWL. Late Seroma in Breast Implants: A Coronavirus Disease 2019 Phenomenon? Arch Plast Surg. 2022 Sep 23;49(5):611-613. doi: 10.1055/s-0042-1756295. PMID: 36159375; PMCID: PMC9507605

Chan SLS, Wong MZ, Tan BK. An Anatomical and Histological Study of the Vastus Lateralis Muscle Nerve and Application for Functional Muscle Transfer in Upper Lip Reconstruction. Journal of Plastic and Reconstructive Surgery 2022. 1. 10.53045/jprs.2021-0024

Chan SLS, Gogna, A., Chui, C.H.K, Wong MZ. Complete Lymphatic Restoration by Simultaneous Vascularised Lymph Node and Lymphatic Vessel Transplantation. European Journal of Plastic Surgery 44, 687-697 (2021)

Chan SLS, Rutherford C, Kong TY. No-drain Technique in Abdominal Closure for Breast Reconstruction: Lower Complication Rate, Shorter Hospitalization Stay. Plast Reconstr Surg Glob Open. 2020 Feb 6;8(2):e2637. doi: 10.1097/GOX.0000000000002637. PMID: 32309084; PMCID: PMC7159947
Singh A, Yazid NBM, Morales RF, Ejima K, Chia PY, Fong SW, Ng LFP, Renia L, Lye DC, Sun LJ, Tan SY, Chai LYA, Kalimuddin S, Young BE, Yeo TW, Teo A. Early neutrophil responses are potential biomarkers to predict severe COVID-19 in adults. J Leukoc Biol. 2025 Mar 20:qiaf035. doi: 10.1093/jleuko/qiaf035. Epub ahead of print. PMID: 40111183.

Siempos II, Kalil AC, Belhadi D, Veiga VC, Cavalcanti AB, Branch-Elliman W, Papoutsi E, Gkirgkiris K, Xixi NA, Kotanidou A, Hermine O, Porcher R, Mariette X; CORIMUNO-19 Collaborative Group; DisCoVeRy Study Group; ACTT-2 Study Group; ACTT-3 Study Group. Immunomodulators for immunocompromised patients hospitalized for COVID-19: a meta-analysis of randomized controlled trials. EClinicalMedicine. 2024 Feb 9;69:102472. doi: 10.1016/j.eclinm.2024.102472. PMID: 38361992; PMCID: PMC10867612.

Lin QXX, Rajagopalan D, Gamage AM, Tan LM, Venkatesh PN, Chan WOY, Kumar D, Agrawal R, Chen Y, Fong SW, Singh A, Sun LJ, Tan SY, Chai LYA, Somani J, Lee B, Renia L, Ng LFP, Ramanathan K, Wang LF, Young B, Lye D, Singhal A, Prabhakar S. Longitudinal single cell atlas identifies complex temporal relationship between type I interferon response and COVID-19 severity. Nat Commun. 2024 Jan 18;15(1):567. doi: 10.1038/s41467-023-44524-0. PMID: 38238298; PMCID: PMC10796319.

Fong SW, Goh YS, Torres-Ruesta A, Chang ZW, Chan YH, Neo VK, Lee B, Duan K, Amrun SN, Yeo NK, Chen HV, Tay MZ, Carissimo G; COVID-19 Study Group; NCID Study Group; Tan SY, Leo YS, Lye DC, Renia L, Young BE, Ng LFP. Prolonged inflammation in patients hospitalized for coronavirus disease 2019 (COVID-19) resolves 2 years after infection. J Med Virol. 2023 May;95(5):e28774. doi: 10.1002/jmv.28774. PMID: 37212320.

Jeyabalan SV, Tay TR, Tan SY, Kumar R. Successful treatment of acute liver failure secondary to dengue fever using low-volume plasma exchange. Singapore Med J. 2023 Mar 13. doi: 10.4103/singaporemedj.SMJ-2021-165. Epub ahead of print. PMID: 36926748.

Goh YS, Fong SW, Hor PX, Amrun SN, Lee CY, Young BE, Chia PY, Tambyah PA, Kalimuddin S, Pada S, Tan SY, Sun LJ, Chen MI, Leo YS, Lye DC, Ng LFP, Renia L. Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections. Front Microbiol. 2022 Nov 22;13:1043049. doi: 10.3389/fmicb.2022.1043049. PMID: 36483199; PMCID: PMC9723332.

Tan CW, Chia WN, Zhu F, Young BE, Chantasrisawad N, Hwa SH, Yeoh AY, Lim BL, Yap WC, Pada SKMS, Tan SY, Jantarabenjakul W, Toh LK, Chen S, Zhang J, Mah YY, Chen VC, Chen MI, Wacharapluesadee S, Sigal A, Putcharoen O, Lye DC, Wang LF. SARS-CoV-2 Omicron variant emerged under immune selection. Nat Microbiol. 2022 Nov;7(11):1756-1761. doi: 10.1038/s41564-022-01246-1. Epub 2022 Oct 4. PMID: 36195753.

Ko HL, Zhuo N, Chang ZW, Santosa A, Kalimuddin S, Lim XR, Tan SY, Lye DC, Toh D, Young BE, Renia L, Lee HY, Ren EC. In vitro vaccine challenge of PBMCs from BNT162b2 anaphylaxis patients reveals HSP90α-NOD2-NLRP3 nexus. Allergy. 2023 Jan;78(1):304-307. doi: 10.1111/all.15503. Epub 2022 Sep 10. PMID: 36056775.

Lee IR, Tong SYC, Davis JS, Paterson DL, Syed-Omar SF, Peck KR, Chung DR, Cooke GS, Libau EA, Rahman SBA, Gandhi MP, Shi L, Zheng S, Chaung J, Tan SY, Kalimuddin S, Archuleta S, Lye DC. Early oral stepdown antibiotic therapy versus continuing intravenous therapy for uncomplicated Gram-negative bacteraemia (the INVEST trial): study protocol for a multicentre, randomised controlled, open- label, phase III, non-inferiority trial. Trials. 2022 Jul 19;23(1):572. doi: 10.1186/s13063-022-06495-3. PMID: 35854360; PMCID: PMC9295110.

Wang LF, Tan CW, Chia WN, Zhu F, Young B, Chantasrisawad N, Hwa SH, Yeoh AY, Lim BL, Yap WC, Pada SK, Tan SY, Jantarabenjakul W, Chen S, Zhang J, Mah YY, Chen V, Chen M, Wacharapluesadee S; COMMIT-KZN Team; Putcharoen O, Lye D. Differential escape of neutralizing antibodies by SARS-CoV-2 Omicron and pre-emergent sarbecoviruses. Res Sq [Preprint]. 2022 Feb 23:rs.3.rs-1362541. doi: 10.21203/rs.3.rs-1362541/v1. PMID: 35233568; PMCID: PMC8887082.

Tan SY, How CH, Poon BH, Tan TY, Siau C. Rostered Routine Testing: A Necessary Evil? Open Forum Infect Dis. 2021 Nov 3;9(1):ofab549. doi: 10.1093/ofid/ofab549. PMID: 35024370; PMCID: PMC8689919.

Tay MZ, Rouers A, Fong SW, Goh YS, Chan YH, Chang ZW, Xu W, Tan CW, Chia WN, Torres-Ruesta A, Amrun SN, Huang Y, Hor PX, Loh CY, Yeo NK, Wang B, Ngoh EZX, Salleh SNM, Chavatte JM, Lim AJ, Maurer-Stroh S, Wang LF, Lin RVTP, Wang CI, Tan SY, Young BE, Leo YS, Lye DC, Renia L, Ng LF. Decreased memory B cell frequencies in COVID-19 delta variant vaccine breakthrough infection. EMBO Mol Med. 2022 Mar 7;14(3):e15227. doi: 10.15252/emmm.202115227. Epub 2022 Jan 21. PMID: 34994081; PMCID: PMC8899913.

Lim J, Puan KJ, Wang LW, Teng KWW, Loh CY, Tan KP, Carissimo G, Chan YH, Poh CM, Lee CY, Fong SW, Yeo NK, Chee RS, Amrun SN, Chang ZW, Tay MZ, Torres-Ruesta A, Leo Fernandez N, How W, Andiappan AK, Lee W, Duan K, Tan SY, Yan G, Kalimuddin S, Lye DC, Leo YS, Ong SWX, Young BE, Renia L, Ng LFP, Lee B, Rötzschke O. Data-Driven Analysis of COVID-19 Reveals Persistent Immune Abnormalities in Convalescent Severe Individuals. Front Immunol. 2021 Nov 19;12:710217. doi: 10.3389/fimmu.2021.710217. PMID: 34867943; PMCID: PMC8640498.

Chia PY, Ong SWX, Chiew CJ, Ang LW, Chavatte JM, Mak TM, Cui L, Kalimuddin S, Chia WN, Tan CW, Chai LYA, Tan SY, Zheng S, Lin RTP, Wang L, Leo YS, Lee VJ, Lye DC, Young BE. Virological and serological kinetics of SARS-CoV-2 Delta variant vaccine breakthrough infections: a multicentre cohort study. Clin Microbiol Infect. 2022 Apr;28(4):612.e1-612.e7. doi: 10.1016/j.cmi.2021.11.010. Epub 2021 Nov 23. PMID: 34826623; PMCID: PMC8608661.

Wang B, Goh YS, Prince T, Ngoh EZX, Salleh SNM, Hor PX, Loh CY, Fong SW, Hartley C, Tan SY, Young BE, Leo YS, Lye DC, Maurer-Stroh S, Ng LFP, Hiscox JA, Renia L, Wang CI. Resistance of SARS-CoV-2 variants to neutralization by convalescent plasma from early COVID-19 outbreak in Singapore. NPJ Vaccines. 2021 Oct 25;6(1):125. doi: 10.1038/s41541-021-00389-2. PMID: 34697298; PMCID: PMC8546091.

Chan YH, Young BE, Fong SW, Ding Y, Goh YS, Chee RS, Tan SY, Kalimuddin S, Tambyah PA, Leo YS, Ng LFP, Lye DC, Renia L. Differential Cytokine Responses in Hospitalized COVID-19 Patients Limit Efficacy of Remdesivir. Front Immunol. 2021 Jun 28;12:680188. doi: 10.3389/fimmu.2021.680188. PMID: 34262564; PMCID: PMC8275132.

Ong SWX, Fong SW, Young BE, Chan YH, Lee B, Amrun SN, Chee RS, Yeo NK, Tambyah P, Pada S, Tan SY, Ding Y, Renia L, Leo YS, Ng LFP, Lye DC. Persistent Symptoms and Association With Inflammatory Cytokine Signatures in Recovered Coronavirus Disease 2019 Patients. Open Forum Infect Dis. 2021 Apr 2;8(6):ofab156. doi: 10.1093/ofid/ofab156. PMID: 34095336; PMCID: PMC8083585.

Chan YH, Fong SW, Poh CM, Carissimo G, Yeo NK, Amrun SN, Goh YS, Lim J, Xu W, Chee RS, Torres-Ruesta A, Lee CY, Tay MZ, Chang ZW, Lee WH, Wang B, Tan SY, Kalimuddin S, Young BE, Leo YS, Wang CI, Lee B, Rötzschke O, Lye DC, Renia L, Ng LFP. Asymptomatic COVID-19: disease tolerance with efficient anti-viral immunity against SARS-CoV-2. EMBO Mol Med. 2021 Jun 7;13(6):e14045. doi: 10.15252/emmm.202114045. Epub 2021 May 27. PMID: 33961735; PMCID: PMC8185544.

Young BE, Wei WE, Fong SW, Mak TM, Anderson DE, Chan YH, Pung R, Heng CS, Ang LW, Zheng AKE, Lee B, Kalimuddin S, Pada S, Tambyah PA, Parthasarathy P, Tan SY, Sun L, Smith GJ, Lin RTP, Leo YS, Renia L, Wang LF, Ng LF, Maurer-Stroh S, Lye DC, Lee VJ. Association of SARS-CoV-2 clades with clinical, inflammatory and virologic outcomes: An observational study. EBioMedicine. 2021 Apr;66:103319. doi: 10.1016/j.ebiom.2021.103319. Epub 2021 Apr 8. PMID: 33840632; PMCID: PMC8027908.

Puah SH, Young BE, Chia PY, Ho VK, Loh J, Gokhale RS, Tan SY, Sewa DW, Kalimuddin S, Tan CK, Pada SKMS, Cove ME, Chai LYA, Parthasarathy P, Ho BCH, Ng JJ, Ling LM, Abisheganaden JA, Lee VJM, Tan CH, Lin RTP, Leo YS, Lye DC, Yeo TW; Singapore 2019 novel coronavirus outbreak research team. Clinical features and predictors of severity in COVID-19 patients with critical illness in Singapore. Sci Rep. 2021 Apr 5;11(1):7477. doi: 10.1038/s41598-021-81377-3. PMID: 33820944; PMCID: PMC8021583.

Chia WN, Zhu F, Ong SWX, Young BE, Fong SW, Le Bert N, Tan CW, Tiu C, Zhang J, Tan SY, Pada S, Chan YH, Tham CYL, Kunasegaran K, Chen MI, Low JGH, Leo YS, Renia L, Bertoletti A, Ng LFP, Lye DC, Wang LF. Dynamics of SARS-CoV-2 neutralising antibody responses and duration of immunity: a longitudinal study. Lancet Microbe. 2021 Jun;2(6):e240-e249. doi: 10.1016/S2666-5247(21)00025-2. Epub 2021 Mar 23. Erratum in: Lancet Microbe. 2021 May;2(5):e179. doi: 10.1016/S2666-5247(21)00088-4. PMID: 33778792; PMCID: PMC7987301.

Chioh FW, Fong SW, Young BE, Wu KX, Siau A, Krishnan S, Chan YH, Carissimo G, Teo LL, Gao F, Tan RS, Zhong L, Koh AS, Tan SY, Tambyah PA, Renia L, Ng LF, Lye DC, Cheung C. Convalescent COVID-19 patients are susceptible to endothelial dysfunction due to persistent immune activation. Elife. 2021 Mar 23; 10:e64909. doi: 10.7554/eLife.64909. PMID: 33752798; PMCID: PMC7987341.

Lee CY, Amrun SN, Chee RS, Goh YS, Mak TM, Octavia S, Yeo NK, Chang ZW, Tay MZ, Torres-Ruesta A, Carissimo G, Poh CM, Fong SW, Bei W, Lee S, Young BE, Tan SY, Leo YS, Lye DC, Lin RT, Maurer-Stroh S, Lee B, Wang CI, Renia L, Ng LF. Human neutralising antibodies elicited by SARS-CoV-2 non-D614G variants offer cross-protection against the SARS-CoV-2 D614G variant. Clin Transl Immunology. 2021 Feb 22;10(2):e1241. doi: 10.1002/cti2.1241. PMID: 33628442; PMCID: PMC7899292.

Goh YS, Chavatte JM, Lim Jieling A, Lee B, Hor PX, Amrun SN, Lee CY, Chee RS, Wang B, Lee CY, Ngoh EZX, Wang CI, Young BE, Tambyah PA, Kalimuddin S, Pada S, Tan SY, Sun LJ, Chen MI, Leo YS, Lye DC, Ng LFP, Lin RTP, Renia L. Sensitive detection of total anti-Spike antibodies and isotype switching in asymptomatic and symptomatic individuals with COVID-19. Cell Rep Med. 2021 Feb 16;2(2):100193. doi: 10.1016/j.xcrm.2021.100193. Epub 2021 Jan 16. PMID: 33495757; PMCID: PMC7816583.

Tan SY, Tey HL, Lim ETH, Toh ST, Chan YH, Tan PT, Lee SA, Tan CX, Koh GCH, Tan TY, Siau C. The accuracy of healthcare worker versus self collected (2-in-1) Oropharyngeal and Bilateral Mid-Turbinate (OPMT) swabs and saliva samples for SARS-CoV-2. PLoS One. 2020 Dec 16;15(12):e0244417. doi: 10.1371/journal.pone.0244417. PMID: 33326503; PMCID: PMC7744114.

Kalil AC, Patterson TF, Mehta AK, Tomashek KM, Wolfe CR, Ghazaryan V, Marconi VC, Ruiz-Palacios GM, Hsieh L, Kline S, Tapson V, Iovine NM, Jain MK, Sweeney DA, El Sahly HM, Branche AR, Regalado Pineda J, Lye DC, Sandkovsky U, Luetkemeyer AF, Cohen SH, Finberg RW, Jackson PEH, Taiwo B, Paules CI, Arguinchona H, Erdmann N, Ahuja N, Frank M, Oh MD, Kim ES, Tan SY, Mularski RA, Nielsen H, Ponce PO, Taylor BS, Larson L, Rouphael NG, Saklawi Y, Cantos VD, Ko ER, Engemann JJ, Amin AN, Watanabe M, Billings J, Elie MC, Davey RT, Burgess TH, Ferreira J, Green M, Makowski M, Cardoso A, de Bono S, Bonnett T, Proschan M, Deye GA, Dempsey W, Nayak SU, Dodd LE, Beigel JH; ACTT-2 Study Group Members. Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19. N Engl J Med. 2021 Mar 4;384(9):795-807. doi: 10.1056/NEJMoa2031994. Epub 2020 Dec 11. PMID: 33306283; PMCID: PMC7745180.

Tee LY, Alhamid SM, Tan JL, Oo TD, Chien J, Galinato P, Tan SY, Humaira S, Fong RKC, Puar TH, Loh WJ, Santosa A, Khoo J, Rosario BH. COVID-19 and Undiagnosed Pre-diabetes or Diabetes Mellitus Among International Migrant Workers in Singapore. Front Public Health. 2020 Nov 11;8:584249. doi: 10.3389/fpubh.2020.584249. PMID: 33262970; PMCID: PMC7686043.

Tan SY, Chien JMF, Li J, Teo EK, Tee A. The COVID-19 cohort ward experience: All hands on deck. Clin Infect Pract. 2020 Oct;7:100047. doi: 10.1016/j.clinpr.2020.100047. Epub 2020 Oct 14. PMID: 33073233; PMCID: PMC7553862.

Khoo HWW, Hui TCH, Mohideen SMH, Lee YS, Liew CJY, Kok SSX, Young BE, Ong SWX, Kalimuddin S, Tan SY, Loh J, Chan LP, Poh ACC, Wong SBS, Leo YS, Lye DC, Kaw GJL, Tan CH. Radiographic features of COVID-19 based on an initial cohort of 96 patients in Singapore. Singapore Med J. 2021 Sep;62(9):458-465. doi: 10.11622/smedj.2020142. Epub 2020 Sep 21. PMID: 33047143; PMCID: PMC9251244.

Young BE, Ong SWX, Ng LFP, Anderson DE, Chia WN, Chia PY, Ang LW, Mak TM, Kalimuddin S, Chai LYA, Pada S, Tan SY, Sun L, Parthasarathy P, Fong SW, Chan YH, Tan CW, Lee B, Rötzschke O, Ding Y, Tambyah P, Low JGH, Cui L, Barkham T, Lin RTP, Leo YS, Renia L, Wang LF, Lye DC; Singapore 2019 Novel Coronavirus Outbreak Research Team. Viral Dynamics and Immune Correlates of Coronavirus Disease 2019 (COVID-19) Severity. Clin Infect Dis. 2021 Nov 2;73(9):e2932-e2942. doi: 10.1093/cid/ciaa1280. PMID: 32856707; PMCID: PMC7499509.

Young BE, Fong SW, Chan YH, Mak TM, Ang LW, Anderson DE, Lee CY, Amrun SN, Lee B, Goh YS, Su YCF, Wei WE, Kalimuddin S, Chai LYA, Pada S, Tan SY, Sun L, Parthasarathy P, Chen YYC, Barkham T, Lin RTP, Maurer-Stroh S, Leo YS, Wang LF, Renia L, Lee VJ, Smith GJD, Lye DC, Ng LFP. Effects of a major deletion in the SARS-CoV-2 genome on the severity of infection and the inflammatory response: an observational cohort study. Lancet. 2020 Aug 29;396(10251):603-611. doi: 10.1016/S0140-6736(20)31757-8. Epub 2020 Aug 18. PMID: 32822564; PMCID: PMC7434477.

Amrun SN, Lee CY, Lee B, Fong SW, Young BE, Chee RS, Yeo NK, Torres-Ruesta A, Carissimo G, Poh CM, Chang ZW, Tay MZ, Chan YH, Chen MI, Low JG, Tambyah PA, Kalimuddin S, Pada S, Tan SY, Sun LJ, Leo YS, Lye DC, Renia L, Ng LFP. Linear B-cell epitopes in the spike and nucleocapsid proteins as markers of SARS-CoV-2 exposure and disease severity. EBioMedicine. 2020 Aug;58:102911. doi: 10.1016/j.ebiom.2020.102911. Epub 2020 Jul 22. PMID: 32711254; PMCID: PMC7375792.

Su YCF, Anderson DE, Young BE, Linster M, Zhu F, Jayakumar J, Zhuang Y, Kalimuddin S, Low JGH, Tan CW, Chia WN, Mak TM, Octavia S, Chavatte JM, Lee RTC, Pada S, Tan SY, Sun L, Yan GZ, Maurer-Stroh S, Mendenhall IH, Leo YS, Lye DC, Wang LF, Smith GJD. Discovery and Genomic Characterization of a 382-Nucleotide Deletion in ORF7b and ORF8 during the Early Evolution of SARS-CoV-2. mBio. 2020 Jul 21;11(4):e01610-20. doi: 10.1128/mBio.01610-20. PMID: 32694143; PMCID: PMC7374062.

Poh CM, Carissimo G, Wang B, Amrun SN, Lee CY, Chee RS, Fong SW, Yeo NK, Lee WH, Torres-Ruesta A, Leo YS, Chen MI, Tan SY, Chai LYA, Kalimuddin S, Kheng SSG, Thien SY, Young BE, Lye DC, Hanson BJ, Wang CI, Renia L, Ng LFP. Two linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patients. Nat Commun. 2020 Jun 1;11(1):2806. doi: 10.1038/s41467-020-16638-2. PMID: 32483236; PMCID: PMC7264175.

Pung R, Chiew CJ, Young BE, Chin S, Chen MI, Clapham HE, Cook AR, Maurer- Stroh S, Toh MPHS, Poh C, Low M, Lum J, Koh VTJ, Mak TM, Cui L, Lin RVTP, Heng D, Leo YS, Lye DC, Lee VJM; Singapore 2019 Novel Coronavirus Outbreak Research Team. Investigation of three clusters of COVID-19 in Singapore: implications for surveillance and response measures. Lancet. 2020 Mar 28;395(10229):1039-1046. doi: 10.1016/S0140-6736(20)30528-6. Epub 2020 Mar 17. PMID: 32192580; PMCID: PMC7269710.

Young BE, Ong SWX, Kalimuddin S, Low JG, Tan SY, Loh J, Ng OT, Marimuthu K, Ang LW, Mak TM, Lau SK, Anderson DE, Chan KS, Tan TY, Ng TY, Cui L, Said Z, Kurupatham L, Chen MI, Chan M, Vasoo S, Wang LF, Tan BH, Lin RTP, Lee VJM, Leo YS, Lye DC; Singapore 2019 Novel Coronavirus Outbreak Research Team. Epidemiologic Features and Clinical Course of Patients Infected With SARS-CoV-2 in Singapore. JAMA. 2020 Apr 21;323(15):1488-1494. doi: 10.1001/jama.2020.3204. Erratum in: JAMA. 2020 Apr 21;323(15):1510. doi: 10.1001/jama.2020.4372. PMID: 32125362; PMCID: PMC7054855.

Tan SY. Tuberculosis and Melioidosis at Distinct Sites Occurring Simultaneously. Case Rep Infect Dis. 2020 Jan 3;2020:9818129. doi: 10.1155/2020/9818129. PMID: 31984142; PMCID: PMC6964720.

Zheng S, Tan SY, Oh HM. Klebsiella Pneumoniae Visceral Organ Abscesses - Clinical Characteristics. Ann Acad Med Singap. 2019 Feb;48(2):48-54. PMID: 30926976.