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Dr Loh Wann Jia

Dr Loh Wann Jia

MBBS with intercalated BSc (1st class Hons), MRCP (UK), MMed, MCI (NUS)


Changi General Hospital

Specialty: Endocrinology

Conditions Treated by this Doctor:
Diabetes Mellitus , General Endocrinology , Lipid disorders , Obesity .

Clinical Appointments

  • Consultant Endocrinology Changi General HospitalChangi General Hospital

Academic Appointments

  • Clinical Assistant Professor, Duke-NUS Medical School
  • Clinical Lecturer, Yong Loo Lin School of Medicine, National University of Singapore
  • Physician Faculty Member, SingHealth Endocrinology Residency Programme


Dr Loh Wann Jia is a Consultant endocrinologist with the Department of Endocrinology at Changi General Hospital. Dr Loh is deeply involved in research and teaching; her research interests include obesity, diabetes mellitus, lipid and metabolic disorders. In pursuit of expanding her sub-specialty work experience and fostering research collaborations, she underwent a fellowship at London hospitals affiliated with Imperial College London in 2017. Followed by a fellowship at the Royal Perth Hospital in Australia in 2022.


  • Master of Clinical Investigation (MCI) National University of Singapore 2021
  • MRCP (UK) 2011
  • MMed (Singapore) 2011
  • MBBS Imperial College London 2008
  • Bachelor of Science (BSc) Endocrinology Imperial College London 2008

Professional Appointments and Committee Memberships

  • Consultant, Department of Endocrinology, Changi General Hospital 2016 – Present
  • Member, Obesity Multidisciplinary Team, Changi General Hospital 2016 – Present
  • Co-lead, Specialist (Diabetes) care, SingHealth Duke-NUS Diabetes Centre (SDDC) Feb 2022 – Present
  • Secretary, Singapore Association of Obesity (SASO) 2019 – 2021
  • Core Faculty, Post-graduate Year 1 (PGY1) March 2020 – 30 Sept 2021
  • Clinical Assistant Professor, Duke-NUS Medical School Sept 2020 – Present
  • Clinical Lecturer, Yong Loo Lin School of Medicine, National University of Singapore June 2018 –Present
  • Physician Faculty Member, SingHealth Endocrinology Residency Programme March 2018 – Present


  • Star Award, Singapore Quality Service Awards, 2023
  • SingHealth Publish! Award, SingHealth, 2022
  • Nurturing Clinician Researcher (NCRS) Award, SingHealth Duke-NUS Medicine ACP grant, April 2022
  • Gold Award, Singapore Health Quality Service Award, SingHealth, 2022
  • Health Manpower Development Plan (HMDP) Award, Ministry of Health, 2021 – 2022
  • Special Recognition Award, National University of Singapore, 2020 – 2021
  • MedACP Teaching Category Senior Educator Award, 2021
  • RISE Awards, Outstanding Faculty Award, 2020
  • Silver Award, Commendable Service Quality Award, SingHealth, 2020
  • RISE Awards, Outstanding Faculty Award, 2017 – 2018
  • Silver Award, Commendable Service Quality Award, SingHealth, 2017

Research Interests

  • Lipid disorder
  • Obesity
  • Diabetes
  • Metabolism


  • Wann Jia Loh* and Gerald F Watts. The Management of Hypercholesterolemia in Patients with Neuromuscular Disorder. Current Atherosclerosis Reports. Dec 2022 PMID: 36609642 DOI: 10.1007/s11883-022-01077
  • Wann Jia Loh* and Gerald F Watts . Xenosterolemia in clinical practice: what is in a name? Current Opinion in Endocrinology & Diabetes and Obesity. PMID: 36597814   DOI: 10.1097/MED.0000000000000795 December 2022
  • Wann Jia Loh* and Gerald F Watts . Detection strategies for elevated lipoprotein(a): will implementation let the genie out of the bottle? Current Opinion in Endocrinology & Diabetes and Obesity ():10.1097/MED.0000000000000789, December 06, 2022. | DOI: 10.1097/MED.0000000000000789 PMID: 36468313 December 2022
  • Chong Boon Teo , Ming Yi Gan , Ryan Yong Kiat Tay , Wann Jia Loh , Ne-Hooi Will Loh Association of preoperative hyponatremia with surgical outcomes: a systematic review and meta-analysis of 32 observational studies. JCEM   PMID: 36472931 DOI: 10.1210/clinem/dgac685 December 2022
  • Paul Nestel, Wann Jia Loh, Natalie C Ward, Gerald F New Horizons: Revival of Lipoprotein(a) as a Risk Factor for Cardiovascular Disease. JCEM. PMID: 36108076 Nov 2022
  • Wann Jia Loh*, R Bakthavachalam, T Subramaniam, S Pek, F Chua, L Lee and Gerald Watts Chylomicronemia through a burr hole: A case report. Frontiers in Cardiovascular Medicine. October 2022 PMID 36312279
  • Natalie Ward, Wann Jia Loh, Gerald F Watts Endothelial dysfunction in type 2 diabetes, with an update on new interventions. Book Chapter in Lipoprotein and Diabetes-Edition II (published 2023)
  • CB Teo, PY Tan, Yong Ryan, Joan Khoo, Gerald Watts, Wann Jia Loh*. Association Between Vitamin D   Supplementation and Statin-Associated Muscle Symptoms: A Systematic Review, 29 June 2022 Journal: High Blood Pressure and Cardiovascular Prevention, 29,337-351(2022)
  • Puar TH, Cheong CK, Foo RSY, Saffari SE, Tu TM, Chee MR, Zhang M, Ng KS, Wong KM, Wong A, Ng FC, Aw TC, Khoo J, Gani L, King T, Loh Wann Jia, Soh SB, Au V, Tay TL, Tan E, Mae L, Yew J, Tan YK, Tong KL, Lee S, Chai. Treatment of Primary Aldosteronism and Reversal of Renin Suppression Improves Left Ventricular Systolic Function. Frontier Endocrinology (Lausanne). 2022 Jun 30;13:916744. doi: 10.3389/fendo.2022.916744. 2022.PMID: 35846272
  • Wann Jia Loh*, Dick Chan, Pedro Mata and Gerald Familial hypercholesterolemia and elevated lipoprotein(a): cascade testing and other implications for contextual models of care ,published 27 Apr 2022. Frontiers in Genetics, Research topic: Genetics of Familial Hypercholesteroemia: New Insight-Volume II
  • Lynette Lee, Sarah Tan and Wann Jia Loh .High urinary sodium concentrations in severe SIADH: case reports of 2 patients and literature review.  Frontiers in Medicine, section Nephrologyàaccepted 16 April 2022
  • Chong Boon Teo, Pek Yan Tan, Shan Xian Lee, Joan Khoo, Jun Guan Tan, Su Fen Ang, Sze Hwa Tan, Tunn Lin Tay, Eberta Tan, Su Chi Lim, Bernhard Otto Boehm, Wann Jia Loh*.  Insulin Allergy to Detemir Followed by Rapid Onset of Diabetic Ketoacidosis: A Case Report and Literature Review. Frontiers in Endocrinology, section Clinical Diabetes, 08 March 2022
  • Wann Jia Loh and Gerald F Watts: Inherited Hypercholesterolemias . Chapter in Endocrinology and Metabolism Clinics of North America -in Press July 2022
  • WJ Loh, Chang X, Aw TC, SK Phua, A F Low, Mark C, G Watts, CK Heng Lipoprotein(a) as predictor of coronary artery disease and myocardial infarction in a multi-ethnic Asian population. Atherosclerosis - Nov 2021 PMID: 34887076
  • Clara Tan, SF Ang, BX Goh, Wann Jia Loh……… CF Sum, Su Chi Lim. MODY5 Hepatocyte Nuclear Factor 1 (HNF1β)-associated nephropathy: experience from a regional monogenic diabetes referral center in Singapore . PMID: 35038894 DOI: 10.1177/23247096211065626 Journal of Investigative Medicine High Impact Case Reports -accepted Dec 2021
  • Fengjie Tang, LM Loh, Roger S. Foo, 3,4 Wann J. Loh. …….. Troy Puar By Tolerability and Efficacy of Long Term Medical Therapy in Primary Aldosteronism. Journal of the Endocrine Society, Nov 2021
  • YK Tan, ….. Wann Jia Loh…… Troy Puar Improvement in Quality of Life and Psychological Symptoms After Treatment for Primary Aldosteronism: Asian Cohort Study. Endocrine Connections July 2021, PMID: 34223820
  • Wann Jia Loh, Lily Mae Dacay, Clara Si Hua Tan, Su Fen Ang, Fabian Yap, Su Chi Lim, Joan Khoo. Glucokinase activating mutation causing hypoglycaemia diagnosed late in adult who fasts for Ramadhan Endocrinology, Diabetes Metabolism Case Reports June 2021 PMID 34184638
  • Yvonne Chan, LM Loh, Roger Foo, Wann Jia Loh…. Peng Chin Kek, Troy Puar Re-evaluating absent clinical success after adrenalectomy in unilateral primary aldosteronism .Surgery, PMID 34183182 25 June 2021
  • Louis Tee, Sharifah….. Wann Jia Loh,….Barbara Rosario. COVID19 and undiagnosed pre-diabetes or diabetes mellitus among international migrant workers in Singapore. Frontiers in Public Health ,PMID33262970 Nov 2020
  • Puar TH, Loh LM, Loh Wann Jia, Dawn Lim, Zhang MF…. Roger Foo.Outcomes in unilateral primary aldosteronism after surgical or medical therapy. Clinical Endocrinology Oct 2020, PMID 33058182
  • Chua TH,and Loh Wann Jia. Osmotic Demyelination syndrome in a patient with Noonan syndrome and anterior hypopituitarism.Endocrinology, Diabetes, Metabolism Case Report 2020 Aug PMID 32820141
  • Kangqi Ng, Beng Hoong Poon, Troy Hai Kiat Puar, Jessica Li Shan Quah, Wann Jia Loh, Yu Jun Wong, Thean Yen Tan, Jagadesan Raghuram. COVID-19 and the Risk to Health Care Workers: A Case Report Annals of Internal Medicine March 2020 PMC7081171
  • Wann Jia Loh, Louise Hughes, David Thai Chong Chua, Linsey GaniA Case Report of Mixed Osteomalacia and Low Bone Density from Vitamin D Deficiency as a Cause of Bilateral Tibial Stress Fractures in a Young Male Military Recruit from Singapore. Case Report of Endocrinology Jan 2020
  • Puar TH, Loh WJ, Lim DS, Loh LM, Zhang M, Foo RS, Lee L, Swee DS, Khoo J, Tay D, Kam JW, Dekkers T, Velema M, Deinum J, Kek PC. Dec 2019, PMID 31851033 Aldosterone--potassium ratio predicts primary aldosteronism subtype. Journal of Hypertension 2019
  • Wann Jia Loh, John Stevenson, Ian Godsland Independent relationships between bone mineral density, regional body fat and insulin sensitivity in white males. Date 2019 Jul;91(1):63-71. doi: 10.1111/cen.13989. Epub 2019 Apr 24. PMID30973644 Clinical Endocrinology
  • Wann Jia Loh, DST Lim, LM Loh, PC Kek Factors Associated with Resolution of Hypertension after Adrenalectomy in Patients with Primary Aldosteronism. Date: Sep 2018 ;33(3):355.363.doi:10.3803/EnM.2018.33.3.355. Epub 2018 Aug 14. PMID:3011286 Endocrinology and Metabolism (Seoul)
  • Loh WJ, Johnston DG, Oliver N, Godsland IF. Skinfold thickness measurements and mortality in white males during 27.7years of follow-up Date : 20 feb 2018 doi:10.1038/s41366-018-0034-0 PMID: doi: 10.1038/s41366-018-0034-4. International Journal of Obesity (2018). PMID29491491
  • Wei Lin Tay, Wann Jia Loh, LAL Lee, Chiaw Ling Chng By Persistent hyperthyroidism and de novo Graves' ophthalmopathy after total thyroidectomy. Date Oct 13 2017 pii: 17-0109. doi: 10.1530/EDM-17-0109 Endocrinology, Diabetes and Metabolism Case Reports PMID: 29062485
  • Wei Lin Tay, Wann Jia LOH, Peng Chin Kek. A case of pembrolizumab-induced type 1 diabetes mellitus presenting with severe diabetic ketoacidosis. Date: 31 July 2017 Journal of clinical and Translational Endocrinology: case reports 6(2017) 9-10
  • Loh Wann Jia, Yu Yue, Loo Chian Min, Low Su Ying. By Factors associated with Mortality among Patients with Active Pulmonary Tuberculosis requiring intensive care ,Date: June 2016 Singapore Medical Journal    PMID:27653545 DOI: 10.11622/smedj.2016160
  • Loh Wann Jia, Chan Weng Hoong, Tham Kwang Wei. Torsion of the Wandering Spleen and Pancreatic Tail. Precipitating Diabetic Ketoacidosis in a Patient with Prader Willi Syndrome, Date: 16 February 2016.Journal of the ASEAN Federation of Endocrine Societies (JAFES)
  • Wee Ming Peh, Wann Jia LOH, Ghee Chee Phua, Chian Min Loo Eliminating guidewire retention during ultrasound guided central venous catheter insertion via an educational program, a modified CVC set, and a drape with reminder stickers, Date: 12 February 2016. Journal: BMJ Quality Improvement Report 2016 PMID:27493743 doi:10.1136/bmjquality.u209550.w3941
  • Loh Wann Jia, Kesavan Sittampalam, Tan Suan Cheng, Manju Chandran.'Symptomatic Empty Sella Syndrome– An unusual manifestation of Erdheim-Chester Disease. Endocrinology, Diabetes and Metabolism Case Reports Date: 2015.PMID:25810917, doi: 10.1530/EDM-14-0122
  • LOH Wann Jia, North BV, Johnston DG, Godsland IF. By Insulin resistance-related biomarker clustering and subclinical inflammation as predictors of cancer mortality during 21.5 years of follow-up. Journal: Cancer Causes Control Date: May 2010PMID:20072808, doi: 10.1007/s10552-009-9499-4

Research Trials