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Vaginal Estradiol (Vagifem)

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Vaginal Estradiol (Vagifem) - Dosage and How to Use

How should Vaginal Estradiol (Vagifem) be used?

  • Vagifem® comes as a vaginal tablet contained in a disposable applicator. 
  • Insert the vaginal tablet into your vagina with the help of the applicator.
  • Unless otherwise instructed by the doctor, insert 1 tablet daily into your vagina for 2 weeks continuously, followed by 1 tablet two times a week. When using it twice a week, leave a 3 – 4 days gap between each dose (for example, Mondays and Thursdays or Tuesdays and Fridays).
  • Do not stop using your medication without checking with your healthcare professional.

Step 1:
  • Tear off one single blister pack and open at the plunger end (push button). Remove the applicator from the plastic wrap as shown.
  • The tablet is at the other end of the applicator.
  • Keep your hands clean and dry to avoid getting the tablet wet.

Step 2:
  • Select the best position for inserting Vagifem® - standing with one foot on a chair or lying on your back.
  • Insert the applicator, with the tablet at the end, into the vagina as far as comfortably possible or until resistance is met (8 – 10cm).
  • Take care not to press the push button at the end until the applicator is inserted properly.

​Step 3:
  • Press the push button at the end of the applicator until a click is felt. This indicates that the tablet has been released from the end of the applicator into the vagina.
  • The tablet will stick to the vagina wall straight away
  • It will not fall out if you stand up or walk. 

​Step 4:
  • Remove and throw away the applicator.

What should I do if I miss a dose?

If you forget to take a dose, take it as soon as you remember. Then take your next dose at the usual time. Do not take two doses to make up for the missed dose.

What should I do if I overdose?

  • Updated on 5/31/2022 12:00:00 AM
  • Article contributed by PSS National Medication Information Workgroup PSS National Medication Information Workgroup
The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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