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Drug Class: Commonly Known As: Category:
Adult

Probenecid - Side Effects, Precautions, and Contraindications

What side effects can Probenecid cause?

  • Stomach upset (nausea, vomiting)
    • Take with food to reduce the occurrence of this side effect
  • Headache
  • Sore gums 
  • Flushing (reddening of skin)

Before taking Probenecid , what precautions must I follow?

Inform your healthcare professional if: 

  • You are allergic to this medication or any of the other ingredients of this medication
  • You are pregnant, planning to become pregnant, or breastfeeding 
  • You are taking any other medications, including supplements, traditional medications and herbal remedies. 
  • Medical conditions such as blood disorder, uric acid kidney stone, kidney disease, G6PD (Glucose-6-Phosphate Dehydrogenase) deficiency or peptic ulcer 

What food or medicine must I avoid when I take Probenecid ?

​For patients taking methotrexate, probenecid may increase the effects of methotrexate in the body. Do inform your healthcare provider for further instructions if you are taking methotrexate.  

Reducing purine rich food such as red meat (eg beef), alcohol, organ meat (eg liver,kidney), shellfish, anchovies, sardine. The list is not exhaustive, do seek further advice from your healthcare provider

  • Updated on 7/31/2022 12:00:00 AM
  • Article contributed by Pharmacy Sengkang General Hospital
The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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