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Topical Estrogen (Oestrogel and Divigel)

Drug Class: Commonly Known As: Category:
Oestrogel, Divigel

Topical Estrogen (Oestrogel and Divigel) - Dosage and How to Use

How should Topical Estrogen (Oestrogel and Divigel) be used?

  • Do not stop using your medication without checking with your healthcare professional.
  • There are two types of topical estrogen available – Oestrogel® and Divigel®.
  • The medication should be applied once a day, around the same time each day. 
  • Before using the medication, clean your skin, wash your hands and allow them to dry thoroughly.
  • Oestrogel®:
    • The medication comes in a tube, with a graduated measure (ruler).
    • Unless otherwise directed by the doctor, start with measuring out ½ ruler (1.25g) of the gel and slowly increase to 1 ruler (2.5g) of the gel. 
  • Divigel®:
    • The medication comes in sachets.
    • Open the sachet and squeeze out the contents onto the skin.
  • Apply the medication to the skin of the outer upper arms, lower part of the stomach or the right or left thigh.
  • The medication should be applied over a large surface, about 1 – 2 times the size of your hand.
  • Do not apply the medication to the face, breasts or vaginal area as well as on cuts, scrapes or irritated skin.
  • After the application, allow the gel to dry for a few minutes and do not wash the area for at least one hour. Wash your hands after application.

What should I do if I miss a dose?

If you miss a dose for less than 12 hours, apply as soon as you remember. Then apply your next dose at the usual time. If it is more than 12 hours since you missed the dose, skip the missed dose and apply the next dose at the usual time. Do not apply two doses to make up for the missed dose.

Sometimes, a missed dose may cause breakthrough bleeding (unexpected bleeding). 

What should I do if I overdose?

  • Updated on 5/31/2022 12:00:00 AM
  • Article contributed by PSS National Medication Information Workgroup PSS National Medication Information Workgroup
The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth


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