Malignant MS tumours can present with one or more of the three main features-

• pain
• A mass ( swelling )
• And a fracture in the case of bone tumour.
  

A particularly worrisome picture will be that of a mass in the extremity or trunk in a teenager that is persistently painful, even while at rest or at night.

Bone tumours are common around the growing regions of the skeleton, such as shoulders and knees.

Soft tissue tumours can be found in both the body or limbs ; but about 50 % of the soft tissue sarcomas are found in the thigh.