​Research Facilities & Capbilities
CTRU occupies an entire ward with a floor area of 835 sq m. It is an air-conditioned, cosy unit that can house 20 clinical trial subjects for overnight stays. It is a perfect setting for the conduct of Pharmacokinetics, Pharmacogenetics and Bioequivalent studies.
The facilities include:
- Dedicated 20 beds
- Synchronised digital clock in every room
- Sample handling laboratory with refrigerated centrifuges
- Refrigerators and freezers for drug and sample storage
- Wireless temperature monitoring system for all refrigerators, freezers and IMP room
- Cardiac telemetry system (Philip Intellive 2.4) with 20 individual portable transmitters
- YSI 2300 STAT Plus system for glucose clamp studies
- Pharmaceutical Isolator for drug compounding
Research Laboratory
The Research Laboratory occupies a floor area of 192 sq m. It provides bench-work support for investigator-led studies and sponsored trials. It also offers consultative services for the design of research studies. It is currently involved in a broad spectrum of research in various disciplines such as microbiology, gastroenterology, cardiology and endocrinology.
The facilities include:
- Genetic analyzer
- PCR thermocyclers
- Gel electrophoresis and imager
- Elisa plate reader
- Triple Quadrupole Liquid Chromatography Mass Spectrometry
- Microscopes
- Biosafety cabinets for sample processing
- Incubators
- Refrigerated centrifuges
- Refrigerators and freezers for sample storage
Research Capabilities
- Development and Validation of LC-MS/MS methods specific to sample matrix and analytes of interest
- Targeted quantification of metabolites (e.g., amino acids, drugs etc) and protein markers.
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Pharmacogenetics and ethnicity studies:
- Consultative services
- Genotyping and phenotyping services
- Building pharmacogenetic database
- Population pharmacokinetic-pharmacodynamic modeling
- Pharmacometrics modeling
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