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Clinical Trial Facility

 


CTRU occupies an entire ward with a floor area of 835 sq m. It is an air-conditioned, cosy unit that can house 20 clinical trial subjects for overnight stays. It is a perfect setting for the conduct of Pharmacokinetics, Pharmacogenetics and Bioequivalent studies.

This facility was developed in consultation with Prof Edmund Lee, Clinical Pharmacologist, National University of Singapore.

The essential equipment and facilities in place include refrigerated centrifuge, -70oC freezer with Uninterrupted Power Supply and auto-paging system, Cardiac Telemetry System, Synchronized digital clocks in every room, ice-maker and ice-shredder.

Other equipment such as EEG telemetry can be set up depending on the requirement. This facility operates in accordance to ICH GCP guidelines, with a group of qualified and experienced research nurses. Manpower can be increased according to the demand.

 

Research Laboratory

In line with Singapore’s efforts to promote life sciences research and development, CGH opened its new research laboratory on 29 January 2002 to further facilitate clinicians and fellow researchers engaged in research activities. With this addition, the total floor area of the research laboratory has expanded to more than 170 square metres in size.

Within this laboratory, research into the Herpes Simplex Virus (HSV), Chlamydia, Mycoplasma and other pathogens have been performed using the latest detection techniques, including enzyme linked immunosorbent assay (ELISA) and polymerase chain reaction (PCR) techniques.


Notwithstanding the research into infectious diseases, explorations into the fields of serology, clinical epidemiology and the culture and detection of Helicobacter pylori have also been conducted. This research in particular has further elucidated the role of this bacterium in peptic ulcer disease and gastric carcinoma.

Our researchers at CGH have been carrying out collaborative research projects with other local and international research entities. Their efforts have been recognized and their works published in various international journals.

 

Clinical Trial Specialties


The unit operates in accordance to ICH GCP guidelines. It has the infrastructure and capabilities to support the conduct of phase I, II, III and IV clinical trials.

Clinical Trial Specialties (Phase I – IIA)

  • Pharmacokinetics, pharmacokinetics-pharmacodynamics study
  • Pharmacogenetics study
  • Bioequivalence study
  • Ethnic sensitivity testing, age and gender effects, food effect, drug effect, and interactions, organ dysfunctions, prolonged QTc

Clinical Trial Specialties (Phase II-IV)

  • Anaesthesia
  • Cardiology
  • Dermatology
  • Endocrinology
  • Gastroenterology
  • Gerontology
  • Hepatology
  • Infectious Diseases
  • Ophthalmology
  • Orthopaedics
  • Otorhinolaryngology
  • Psychological Medicine
  • Respiratory Medicine
  • Surgery
  • Urology

 

Contact Us

Clinical Trials & Research Unit
Changi General Hospital
2 Simei Street 3, Singapore 529889

Tel: (65) 6850 1900/ 1990
Fax: (65) 6788 1396

Email: lay_hwa_yew@cgh.com.sg

Designation Name Telephone (Pager) E-mail
Advisor Prof Fock Kwong Ming 68503987 kwong_ming_fock@cgh.com.sg
Visiting Consultant Prof Edmund J.D. Lee 68501900 edlee@nus.edu.sg
Head Dr Hsu Pon Poh 68503787 pon_poh_hsu@cgh.com.sg
Manager Ms Yew Lay Hwa 68502375 (81211501) lay_hwa_yew@cgh.com.sg
Research Scientist Dr S Dhamodaran 68504929 (97694926) s_dhamodaran@cgh.com.sg
Snr Co-ordinator Ms Yap Siew Yoon 68502935 (96502443) siew_yoon_yap@cgh.com.sg
Co-ordinator Ms Soon Sou Yen 68502923 (81258214) sou_yen_soon@cgh.com.sg
Co-ordinator Ms Chan Pui Min 68501993 (81211265) pui_min_chan@cgh.com.sg
Co-ordinator Ms Tan Mui Teng Madeline 68502379 (91278876) madeline_tan@cgh.com.sg
Co-ordinator Ms Tang Xuan 68502537 (81258439) xuan_tang@cgh.com.sg
Co-ordinator Mr Samuel Hong 68501902 (98157250) samuel_hong@cgh.com.sg
Co-ordinator Ms Yap Fui Chin 68502539 (9796328) fui_chin_yap@cgh.com.sg
Medical Technologist Mr Lu Song 68504913 (81258454) song_lu@cgh.com.sg
Snr Admin Asst Ms Goh Li Li 68502538 li_li_goh@cgh.com.sg